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Draadje varkensgriep

1.005 Posts
Pagina: «« 1 ... 6 7 8 9 10 ... 51 »» | Laatste | Omlaag ↓
  1. forum rang 10 voda 29 april 2009 22:27
    Nog geen actie in Nederland na alarmfase 5
    29 april 2009, 22:19 | ANP
    BILTHOVEN (ANP) - De woensdag door de Wereldgezondheidsorganisatie WHO afgekondigde alarmfase 5 voor de Mexicaanse griep geldt ook voor Nederland al gebeurt er voorlopig in ons land nog niets. Dat meldde een woordvoerder van het RIVM woensdag.

    Bij alarmfase 5 mogen de autoriteiten onder andere beginnen met het verspreiden van medicijnen naar bijvoorbeeld apothekers. Omdat in Nederland nog geen besmettingsgevallen zijn, komen de autoriteiten vooralsnog niet in actie.

    Nederland is wel klaar voor een eventuele pandemie of uitbraak van de Mexicaanse griep.

  7. forum rang 10 voda 29 april 2009 23:31
    quote:

    flosz schreef:

    Ik zie het niet zo als paniek, en ga er vooralsnog vanuit dat er een goede reden is om naar phase 5 te gaan... sterker nog, er is waarschijnlijk meer aan de hand dan wij behoren te weten.
    Ik wilde net vragen hoe jij hier over dacht. Wat een toeval zeg.
    Ik ga met je denkwijze mee, hier ligt teveel nadruk op. Het lijkt wel of er juist iets anders aan de hand is?
  8. flosz 29 april 2009 23:32
    quote:

    diederique schreef:

    El presidente interino del Departamento de Seguridad Sanitaria y Medio Ambiente de la OMS,Keiji Fukuda,dijo que tomará entre cuatro y seis meses fabricar y producir la vacuna contra el virus.

    www.diariodemexico.com.mx/?module=dis...
    Zo is het ook volgens Ab Osterhaus, Sanofi 4 mnd.
    Misschien op tijd voor de tweede golf...maar dan, de capaciteit?
  10. ved 29 april 2009 23:36
    quote:

    ved schreef:

    Swine flu: The predictable pandemic?
    29 April 2009 by Debora MacKenzie

    toch langer dan ik dacht;vervolg:

    That's why the CDC warned last year that swine H1N1 would "represent a pandemic threat" if it started circulating in humans.

    The avian polymerase genes are especially worrying, as similar genes are what make H5N1 bird flu lethal in mammals and what made the 1918 human pandemic virus so lethal in people. "We can't yet tell what impact they will have on pathogenicity in humans," says Webby.

    It appears the threat has now resulted in the Mexican flu. "The triple reassortant in pigs seems to be the precursor," Robert Webster, also at St Jude's, told New Scientist.

    While researchers focused on livestock problems could see the threat developing, it is not one that medical researchers focused on human flu viruses seemed to have been aware of. "It was confusing when we looked up the gene sequences in the database," says Wendy Barclay of Imperial College London, who has been studying swine flu from the recent US cases. "The polymerase gene sequences are bird and human, yet they were reported in viruses from pigs."

    So where did the Mexican virus originate? The Veratect Corporation based in Kirkland, Washington, monitors world press and government reports to provide early disease warnings for clients, including the CDC. Their first inkling of the disease was a 2 April report of a surge in respiratory disease in a town called La Gloria, east of Mexico City, which resulted in the deaths of three young children. Only on 16 April - after Easter week, when millions of Mexicans travel to visit relatives - reports surfaced elsewhere in the country.

    Local reports in La Gloria blamed pig farms in nearby Perote owned by Granjas Carroll, a subsidiary of US hog giant Smithfield Foods. The farms produce nearly a million pigs a year.

    Smithfield Foods, in a statement, insists there are "no clinical signs or symptoms" of swine flu in its pigs or workers in Mexico. That is unsurprising, as the company says it "routinely administers influenza virus vaccination to swine herds and conducts monthly tests for the presence of swine influenza." The company would not tell New Scientist any more about recent tests. USDA researchers say that while vaccination keeps pigs from getting sick, it does not block infection or shedding of the virus.

    All the evidence suggests that swine flu was a disaster waiting to happen. But it got little research attention, perhaps because it caused mild infections in people which didn't spread. Now one swine flu virus has stopped being so well-behaved.

    What makes flu go global?
    A "pandemic" is an epidemic that goes global, so technically there is a flu pandemic every year. But the term is usually reserved for bad outbreaks that follow large changes in the virus.

    The influenza virus constantly evolves, and pandemics happen every few decades when the flu virus gets new surface proteins that people have little immunity to, generally because they come from an animal strain. The lack of immunity means the virus affects more people more severely.

    That's why H5N1 bird flu is so dangerous. Its H5 surface protein is totally new to humans, and the virus has killed more than half of the people it infected. It or another bird flu that can infect humans, such as a virus from the H7 or H9 families, only needs to become readily contagious to go pandemic.

    H1N1 has received less attention partly because an H1N1 strain already circulates in humans. The problem is the Mexican strain carries different versions of H1. Still, that alone is not enough to make this virus pandemic.

    It must also transmit efficiently in people. Every victim must infect more than one other person for the virus to spread. The new strain could do this, as it is packing an altogether faster engine than previous H1N1 strains. It has an avian gene that has powered it to dominance in pigs, though no one knows for certain if this will make it dangerous in people.

    www.newscientist.com/article/mg202270...
  13. [verwijderd] 29 april 2009 23:42
    Ok Flosz, maar er moeten niet weer meteen complotten gezocht gaan worden. Daar schijnen beleggers nu eenmaal patent op te hebben.

    Misschien ben ik naief ... we shall see!
    Grt, S

    quote:

    voda schreef:

    [quote=flosz]
    Ik zie het niet zo als paniek, en ga er vooralsnog vanuit dat er een goede reden is om naar phase 5 te gaan... sterker nog, er is waarschijnlijk meer aan de hand dan wij behoren te weten.
    [/quote]
    Ik wilde net vragen hoe jij hier over dacht. Wat een toeval zeg.
    Ik ga met je denkwijze mee, hier ligt teveel nadruk op. Het lijkt wel of er juist iets anders aan de hand is?
  14. flosz 29 april 2009 23:46
    Ik zie dit niet als complot maar als gewone gang van zaken. Degene boven op de bron weet toch altijd meer in vergelijking tot de rest van de wereldbevolking en om daadwerkelijk paniek te voorkomen is dat misschien wel zo verstandig.
    ****************
    Verklaring rechtstreeks van Chan (WHO) en niet via de krant:

    Statement by WHO Director-General, Dr Margaret Chan
    29 April 2009
    Swine influenza
    Ladies and gentlemen,
    Based on assessment of all available information, and following several expert consultations, I have decided to raise the current level of influenza pandemic alert from phase 4 to phase 5.
    Influenza pandemics must be taken seriously precisely because of their capacity to spread rapidly to every country in the world.
    On the positive side, the world is better prepared for an influenza pandemic than at any time in history.
    Preparedness measures undertaken because of the threat from H5N1 avian influenza were an investment, and we are now benefitting from this investment.
    For the first time in history, we can track the evolution of a pandemic in real-time.
    I thank countries who are making the results of their investigations publicly available. This helps us understand the disease.
    I am impressed by the work being done by affected countries as they deal with the current outbreaks.
    I also want to thank the governments of the USA and Canada for their support to WHO, and to Mexico.
    Let me remind you. New diseases are, by definition, poorly understood. Influenza viruses are notorious for their rapid mutation and unpredictable behaviour.
    WHO and health authorities in affected countries will not have all the answers immediately, but we will get them.
    WHO will be tracking the pandemic at the epidemiological, clinical, and virological levels.
    The results of these ongoing assessments will be issued as public health advice, and made publicly available.
    All countries should immediately activate their pandemic preparedness plans. Countries should remain on high alert for unusual outbreaks of influenza-like illness and severe pneumonia.
    At this stage, effective and essential measures include heightened surveillance, early detection and treatment of cases, and infection control in all health facilities.
    This change to a higher phase of alert is a signal to governments, to ministries of health and other ministries, to the pharmaceutical industry and the business community that certain actions should now be undertaken with increased urgency, and at an accelerated pace.
    I have reached out to donor countries, to UNITAID, to the GAVI Alliance, the World Bank and others to mobilize resources.
    I have reached out to companies manufacturing antiviral drugs to assess capacity and all options for ramping up production.
    I have also reached out to influenza vaccine manufacturers that can contribute to the production of a pandemic vaccine.
    The biggest question, right now, is this: how severe will the pandemic be, especially now at the start?
    It is possible that the full clinical spectrum of this disease goes from mild illness to severe disease. We need to continue to monitor the evolution of the situation to get the specific information and data we need to answer this question.
    From past experience, we also know that influenza may cause mild disease in affluent countries, but more severe disease, with higher mortality, in developing countries.
    No matter what the situation is, the international community should treat this as a window of opportunity to ramp up preparedness and response.
    Above all, this is an opportunity for global solidarity as we look for responses and solutions that benefit all countries, all of humanity. After all, it really is all of humanity that is under threat during a pandemic.
    As I have said, we do not have all the answers right now, but we will get them.
    Thank you.
    www.who.int/mediacentre/news/statemen...
  17. [verwijderd] 30 april 2009 00:14
    Adimmune news

    Flu vaccine promise

    Local biopharmaceutical firm Adimmune Corp. officials said yesterday that the company will cancel all existing orders and shift exclusively to the production of a human vaccine against H1N1 swine flu if asked to do so by the government.

    A spokesman said that once Adimmune receives samples of the H1N1 swine flu virus strain, it will be capable of churning out up to 24 million doses of swine flu vaccine in three to six months.

    The expansion of an Adimmune influenza vaccine plant is scheduled to be completed in June and will be capable of producing 30 million doses of flu vaccine a year.
  18. flosz 30 april 2009 00:29
    Bedankt ron.
    ______________
    www.etaiwannews.com/etn/news_content....

    Local pharmaceutical companies prepare to develop swine flu vaccine
    TAIPEI, Taiwan -- Taiwan has been in contact with the United States, seeking samples of the H1N1 swine flu virus strain so that local pharmaceutical companies can start developing a human vaccine against the virus that emerged in Mexico last week, Health Minister Yeh Chin-chuan said Wednesday.

    Yeh said at the Legislative Yuan that the Department of Health (DOH) has also instructed the non-profit National Health Research Institute (NHRI) to prepare for developing the vaccine.
    He said the NHRI is capable of producing vaccine in emergency situations and that an expanded vaccine plant run by Adimmune Corp., also known as Kuo Kwang Biotechnology, is expected to be inaugurated by June.
    The Adimmune vaccine plant, which will be the largest of its kind in Asia with a maximum annual capacity of 30 million doses of vaccine, will allow production of human vaccine against swine flu to be significantly ramped up, Yeh noted.
    Noting that the World Health Organization (WHO) is working on a global H1NI vaccine production plan, Yeh said the country will take part in the global action in line with WHO instructions.
    www.chinapost.com.tw/taiwan/national/...

    Local firm Adimmune Corp said separately yesterday that if asked by the government, it would cancel all orders and produce only H1N1 swine flu vaccine.

    A spokesman said that Adimmune could produce up to 24 million doses of vaccine within three to six months of receiving a sample of the H1N1 strain of swine flu.

    Adimmune, Taiwan’s only private manufacturer of vaccines for humans, produces vaccines for the flu, Japanese encephalitis, tetanus and tuberculosis.
    www.taipeitimes.com/News/taiwan/archi...

    Crucell & ADImmune Corporation.
    www.iex.nl/Forum/topic.asp?forum=228&...
    __________________
    Swine flu information center….van Novartis:
    www.novartis.com/newsroom/swine-flu/
  19. [verwijderd] 30 april 2009 07:14
    Mexicaanse griep treft ook Zwitserland en Peru
    Uitgegeven: 30 april 2009 07:07
    Laatst gewijzigd: 30 april 2009 07:07

    MEXICO-STAD/BERN/LIMA - De Mexicaanse griep is inmiddels opgedoken in elf landen. Ook in Zwitserland en Peru blijken mensen te zijn besmet met de dodelijke ziekte.

    Dat maakten de autoriteiten in de beide landen donderdag (Nederlandse tijd) bekend.

    De Zwitserse patiënt ligt in een ziekenhuis in de noordelijke stad Baden, bij de grens met Duitsland. Hij was onlangs teruggekeerd uit Mexico.

    Peru

    In Peru is een Argentijnse vrouw besmet met het H1N1-virus. Ook zij had een bezoek gebracht aan Mexico. Tijdens de terugvlucht naar de Argentijnse hoofdstad Buenos Aires werd ze ziek, waarop het vliegtuig landde in Peru.

    De vrouw ligt in quarantaine in een ziekenhuis in de havenstad Callao, nabij de Peruviaanse hoofdstad Lima.

    Mexico

    Mexico, waar het virus uitbrak, is het zwaarst getroffen door de griep. De ziekte is inmiddels vastgesteld bij 99 mensen, van wie acht zijn overleden. De Mexicaanse regering houdt echter rekening met ongeveer 2500 besmettingen en spreekt van 176 verdachte sterfgevallen.

    De Europese Commissie vreest dat de Mexicaanse griep ook in Europa mensen het leven zal kosten. Het is niet de vraag of mensen in Europa zullen overlijden, maar hoeveel, zei de topambtenaar voor gezondheidszaken Robert Madelin.

    Spoedberaad

    Om de gevolgen van het virus binnen de perken te houden, komen de 27 Europese ministers van Volksgezondheid donderdagmiddag in Luxemburg bijeen voor een spoedberaad.

    De bewindslieden, onder wie minister Ab Klink namens Nederland, zullen onder meer bekijken of er reisadviezen nodig zijn. Frankrijk heeft erop aangedrongen vluchten naar Mexico voorlopig te schrappen, maar de kans dat de ministers zo'n drastisch besluit nemen, lijkt klein.

    © ANP

  20. flosz 30 april 2009 12:12
    Published online 29 April 2009 | Nature 458, 1082-1083 (2009) | doi:10.1038/4581082a

    Swine flu goes global
    New influenza virus tests pandemic emergency preparedness.
    Declan Butler
    Researchers are scrambling to study the evolution and spread of the novel H1N1 strain of swine influenza whose leap to humans was officially confirmed last week. The possible imminent onset of a swine-flu pandemic is also testing international preparedness plans put into place to deal with something else: the much-feared H5N1 avian flu virus that has spread across Asia, Europe and Africa since 2003.
    The genetic make-up of this swine flu virus is unlike any that researchers have seen. It is an H1N1 strain that combines a triple assortment first identified in 1998 — including human, swine and avian influenza — with two new pig H3N2 virus genes from Eurasia, themselves of recent human origin.
    "It has been mixing all over the place, and so the genetics are quite complicated," says John McCauley, a virologist at the UK Medical Research Council's National Institute for Medical Research in London. "Where the hell it got all these genes from we don't know," says Robert Webster, a flu virologist at St Jude Children's Research Hospital in Memphis, Tennessee. "But this is a real super-mixed-up virus."
    As Nature went to press, more than 150 people were thought to have died from the virus in Mexico, with some 1,600 cases suspected there. At least 87 cases have been confirmed in other countries, including the United States, Canada, New Zealand, the United Kingdom, Spain and Israel.
    On 27 April, the World Health Organization (WHO) raised its pandemic threat from phase 3 — a new flu virus infecting humans but with limited human-to-human spread — to phase 4, with community outbreaks that mark "a significant upwards shift in the risk for a pandemic". The scale runs to 6: a full-blown pandemic.
    "The scary thing is that this virus seems enormously transmissible," says Webster. In New York, for instance, at least 28 students at a school in Queens have come down with it.
    The US Centers for Disease Control and Prevention (CDC) and the WHO are trying to nail down how many of the reported deaths in Mexico are due to swine flu and how many are due to other causes. "The spectrum of illness is still a matter of doubt and conjecture," says David Ozonoff, an epidemiologist at the Boston University School of Public Health in Massachusetts. For instance, rumours swirled that archaeologist Felipe Solis, the director of the National Museum of Anthropology in Mexico City who had met recently with US President Barack Obama, died on 23 April as a result of the swine flu. Mexican authorities later reported he died of cardiac arrest linked to pneumonia.
    No human immunity
    The virus seems to have first taken hold in Mexico in mid-March; it was identified when Mexican authorities sent samples from a flu patient that it could not subtype to the Canadian Public Health Agency. After cases in California, the CDC announced the existence of the virus on 23 April.
    The genetics of the virus are so novel that humans are unlikely to have much immunity to it, scientists say. The current seasonal flu vaccine, which targets a different H1N1 strain, also isn't likely to offer any protection. Discussions are under way as to whether a new vaccine for the swine flu strain should be produced. The WHO has recommended that vaccine makers continue to manufacture the seasonal flu strain but begin thinking about how to manufacture large doses of a vaccine that incorporates a weakened version of the current swine flu strain. For now, the virus is treatable with the influenza drugs oseltamivir (Tamiflu) and zanamivir (Relenza).
    So far, cases in the United States and elsewhere seem to have been relatively mild compared with those in Mexico. Tashiro Masato, a virologist at the National Institute of Infectious Diseases in Tokyo, warns against drawing any conclusions from this. He notes that the sample of cases from the United States is too small to pick up even single-digit mortality rates. If transmission rates turn out to be high (see 'Research questions to answer'), mortality rates of even a few per cent could lead to millions of deaths, as in the pandemic of 1918.
    For the moment the pathogenicity and mortality range is wide and uncertain, says McCauley — "anything between the lethal 1918 and the mild 1968 pandemic". The high transmission rates in areas such as New York are worrying, says Mark Lipsitch, an epidemiologist of the Harvard School of Public Health in Boston, Massachusetts. But a better idea should be forthcoming as testing ramps up, and health authorities get a clearer picture of the ratio of deaths to those infected.
    The new virus, however, comes nowhere near the mortality rates of H5N1, which have averaged around 63% globally and reached as high as 82% in Indonesia. "The risk and threat of H5N1 remain as before", Masato warns.
    Epidemiologists are largely applauding the speed and scale of the response to the swine flu outbreak since it was formally identified last week, even though Mexican and international disease surveillance systems failed to pick it up promptly at the start. Several scientists speculate that the initial cases were months ago and perhaps outside Mexico. Ambitious WHO plans to quickly detect and extinguish an emerging pandemic before it grew, by distributing flu drugs, were thus not useful.
    But once the virus was officially announced, governments have swung into action. The United States, for instance, has released one-quarter of its 50 million stockpiled doses of oseltamivir and zanamivir for treatment in the affected states. The international response is being largely attributed to the amount of pandemic planning undertaken since the threat of a H5N1 pandemic emerged. Gene sequences of the virus samples, for instance, have been promptly shared on the Global Initiative on Sharing Avian Influenza Data (GISAID) database. Sequence information can have practical significance — for example, in designing PCR primers, to make rapid diagnosis tests that broaden and speed up surveillance.
    Many virologists think they are in for the long haul. "Will this fizzle out? It doesn't look like it to me," says McCauley. "For me this is the time to start deploying national pandemic plans. We need to act now."
    www.nature.com/news/2009/090429/full/...
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