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Home  /  Forum  /  Celyad  /  CELYAD 2017 Nieuws

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Aandeel Celyad BRU:CYAD.BL, BE0974260896

  • 0,338 29 apr 2024 10:09
  • +0,003 (+0,90%) Dagrange 0,320 - 0,340
  • 16.987 Gem. (3M) 20,9K

CELYAD 2017 Nieuws

643 Posts
Pagina: «« 1 2 3 4 5 6 ... 33 »» | Laatste | Omlaag ↓
  2. lorcu 28 april 2017 09:38
    Celyad initiates second dose escalation in THINK trial in first US patient
    Initiation of the THINK trial in the US at Roswell Park Cancer Institute
    Dosing of the first patient of the second dose (1x109) in solid tumor arm
    Favorable safety profile reported on all patients treated with CAR-T NKR-2
    Mont-Saint-Guibert, Belgium - Celyad (Euronext Brussels and Paris, and NASDAQ:CYAD), a leader in the discovery and development of engineered cell therapies, today announced the dosing of the first patient of the second dose in the solid tumor arm of its THINK trial (THerapeutic Immunotherapy with NKR-2). This first ovarian cancer patient has been dosed at Roswell Park Cancer Institute (Buffalo, New York).
  4. lorcu 2 mei 2017 09:24

    Celyad grants to Novartis a non-exclusive license for its allogeneic TCR-deficient CAR-T cells patents
    Mont-Saint-Guibert, Belgium - Celyad (Euronext Brussels and Paris, and NASDAQ:CYAD), a leader in the discovery and development of cell therapies, today announced a non-exclusive license agreement with Novartis for Celyad’s US patents for the production of allogeneic CAR-T cells. This license agreement is related to two targets currently under development by Novartis
  14. Zo gaat dat 8 mei 2017 15:01
    Oud berichtje over de deal maar het verwoord één en ander wel duidelijk.

    GEN News Highlights More »
    May 2, 2017
    Novartis, Celyad Agree to Nonexclusive CAR T-Cell Technology Deal
    Belgium-based Celyad granted Novartis a nonexclusive license to its allogeneic chimeric antigen receptor (CAR) T-cell technology for two unspecified Novartis targets. The potentially $96 million deal includes an up-front payment and single-digit royalties on net sales of the products developed using the licensed technology. The deal gives Novartis an option to extend the license to additional targets, and/or to convert it to an exclusive license. Celyad retains the right to grant allogeneic CAR T-cell licenses to other parties.

    Christian Homsy, M.D., CEO of Celyad, commented, "This nonexclusive agreement with Novartis recognizes the importance of our IP for companies developing allogeneic CAR T-cell therapies."

    Celyad is developing its Natural Killer Receptor T-cell (NKR-T) platform for the potential treatment of a range of solid and hematologic tumors. Lead CAR T-cell candidate NKR-2 expresses the human NK receptor NKG2D, which Celyad claims binds to ligands that are expressed on 80% of cancers, giving the product potential utility against both solid and hematologic cancers. The firm is developing both allogenic and autologous NKR-2 products. The allogeneic NKR-2 CAR T-cell product has been successfully evaluated in a Phase I study in patients with acute myeloid leukemia (AML) and multiple myeloma (MM). In March, the firm received FDA clearance to start a second, U.S.- and EU-based open-label Phase Ib study, THINK, in multiple cancer indications, including five solid cancers and two hematological cancers.

    During mid-2016, Celyad and Ono Pharmaceutical inked a potentially $311.5 million deal for the allogeneic NKR-2 T-cell therapy in Japan, Korea, and Taiwan. The agreement includes an exclusive option for Ono to license the autologous KNR-2 T-cell product in the same territories.

    Celyad also has an ongoing NKR-T research collaboration with the Institut Curie in Paris, France, signed in March 2016.

    Celyad has separately been developing its C-Cure® cell therapy for heart failure, and although the European CHART-1 Phase III C-Cure study failed to meet its primary endpoint in mid-2016, the study indicated potential benefits of treatment for specific subsets of patients. Celyad is using the trial data to optimize the design of a second pivotal U.S.-based trial, CHART-2, and is looking for partners to continue C-Cure development and commercialization.

    www.genengnews.com/gen-news-highlight...
643 Posts
Pagina: «« 1 2 3 4 5 6 ... 33 »» | Laatste |Omhoog ↑

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