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word abonnee

Crucell & ADImmune Corporation.

69 Posts
Pagina: «« 1 2 3 4 »» | Laatste | Omlaag ↓
  1. flosz 29 juni 2009 08:48
    Things That Make You Go Hmmmm....

    Mbt de opening van de plant:
    President Ma Ying-jeou attended the new plant’s opening ceremony. In his address, he mentioned that when the company was preparing to establish the new plant last year, no one could ever have imagined the H1N1 outbreak. The heavens have blessed Taiwan, he said.
    taiwanjournal.nat.gov.tw/ct.asp?xItem...

    www.youtube.com/watch?v=D2Dtfi3VkiU&f...
  2. bilbo3 14 juli 2009 21:16
    Adimmune wins tender for A(H1N1) vaccine production

    By Jimmy Chuang
    STAFF REPORTER
    Saturday, Jul 11, 2009, Page 2
    Local biopharmaceutical company Adimmune Corp yesterday won the bid tendered by the Centers for Disease Control (CDC) to become the government’s main supplier of the vaccine against A(H1N1).

    The company will produce 5 million doses of the vaccine by fall that the CDC will purchase at a price of NT$199 each. The delivery date is scheduled for Oct. 30, the CDC said.

    The CDC held its first bidding round on July 3, which flopped because Adimmune was the only bidder.

    Foreign suppliers, already unable to meet demand in international markets and unlikely to be able to comply with the government’s targeted October delivery date, showed no interest in participating in the tenders for the vaccine.

    The Government Procurement Act (政府採購法) states that the first bidding round must have at least three bidders to make it valid but there is no such requirement for the second round.

    “Adimmune was still the only bidder [in the second round,]” CDC spokesman Lin Ting (林頂) said. “We are quite confident that these 5 million doses can be ready [on schedule.]”

    Adimmune has bought 8 million chicken eggs to produce the human vaccine against A (H1N1) using chicken embryos. The company said it has begun the process of producing more than 1.5 doses from one egg, and estimated that it could produce between 7.5 million and 10 million doses of the vaccine with its available egg stocks.

    Lin had previously said the CDC planned to purchase 10 million doses of the (A)H1N1 virus vaccine, 5 million doses of seasonal flu vaccine and 900,000 doses of the antiviral drug Relenza this year to strengthen its anti-pandemic arsenal.

    So far, the CDC has secured 2.28 million doses of vaccine against seasonal flu, including 400,000 doses for children, Lin said.

    www.taipeitimes.com/News/taiwan/archi...
  3. flosz 31 oktober 2009 01:01
    2009/10/15 Guoguang biotech industrie A (H1N1) influenza vaccin eerste dosis van humane klinische studies verzending datum: 2009-10-15 Contactpersoon voor de pers: Hong Shujing (0935101378; sonia789@gmail.com) Kuo Kuang biotech-industrie een (H1N1) influenza vaccin eerste dosis van humane klinische studies, de deelname van de proefpersonen werd vanaf 12 oktober terug naar het ziekenhuis een bloedmonster, op de 17e van de eerste fase van de menselijke studies te voltooien. Bloed testresultaten zullen worden aangekondigd op de 20e kwam, moet verder gaan door middel van drie co-hosts plan van het ziekenhuis aan de validatie voldoen, de National Optical biotechnologie kan de eerste dosis van 21 menselijke resultaten van klinische proeven aan het ministerie van Volksgezondheid, het Ministerie van Volksgezondheid evaluatie van de selectieve operatie. Onderwerpen die deelnemen aan de 12 tot 17, terug naar het ziekenhuis voor bloed, is de ontvangst van de tweede dosis van het vaccin, zal worden teruggestuurd naar het ziekenhuis voor drie weken en dan bloed.
    www.adimmune.com.tw/news/file/2009101...

    DOH hails results of vaccine trials
    Department of Health (DOH) Minister Yaung Chih-liang hailed yesterday at the Legislative Yuan the mid-term results of human clinical testing of A(H1N1) vaccine produced by Adimmune Corp, Taiwan's sole human vaccine manufacturer.
    Fielding questions at a meeting of the legislature's Social Welfare and Environmental Hygiene Committee about the locally produced vaccine, Yaung said the Adimmune vaccine is in no way inferior to an A(H1N1) vaccine marketed by the Swiss-based pharmaceutical firm Novartis.
    Stressing that the initial results have been good, Yaung said, however, that the final results will be made public in two days, after related data has been collated by a DOH pharmaceutical screening committee. According to Kang Chao-chou, chief of the DOH's Bureau of Pharmaceutical Affairs, the screening committee was scheduled to meet the following day to review the mid-term results.
    www.etaiwannews.com/etn/news_content....

    Single shot local H1N1 vaccine will likely suffice
    TAIPEI, Taiwan -- Health authorities are keen on greenlighting a recommended adult A(H1N1) flu vaccine dosage of one shot per person, local media reported yesterday.
    Department of Health (DOH) officials and experts convened yesterday afternoon during a roundtable to discuss results garnered by the first of two clinical studies of locally produced A(H1N1) vaccine in human subjects, said the Central News Agency (CNA).
    The group met to decide whether or not adults will require a booster shot, the report said.
    The number of shots to be received by persons 18 and under will be determined at a later time, the report added.
    According to the United Evening News, vaccinations are slated to be rolled out Nov. 16.
    Officials said preliminary reports of human testing have shown stellar results, with 70 percent immune response developed in adults 18 and older, and as much as 90 percent in young, healthy adults.
    The locally produced vaccine is made by sole vaccine manufacturer Adimmune Corp.
    The company is trying its hand at manufacturing flu vaccine, which has led to public fears and worries of its product.
    Health Minister Yaung Chih-liang had previously noted that locally produced vaccines are comparable to foreign counterparts such as those made by Swiss pharmaceutical giant Novartis.
    The government has purchased 10 million flu shots from Adimmune and another five million from Novartis.
    Children nine years old and younger receiving the Novartis vaccine are required to receive a vaccine shot followed by a booster shot.

    www.chinapost.com.tw/taiwan/national/...
  4. forum rang 4 aossa 16 november 2009 17:30
    Taiwan scores biotech breakthrough with H1N1 vaccine success

    Central News Agency

    By Sofia Wu CNA Staff Writer The influenza A(H1N1) outbreak might present a health threat to the people of Taiwan, but the swine flu virus has also generated a new opportunity for Adimmune, the country's once-troubled sole human vaccine manufacturing company.

    With certification from the Cabinet-level Department of Health (DOH) , Adimmune's H1N1 vaccine will begin to be administered to elementary schoolchildren, preschoolers, pregnant women and seriously ailing or injured patients Nov. 16 in line with a priority list for recipients of free vaccinations.

    In a symbolic gesture of support for the locally developed vaccine, President Ma Ying-jeou is scheduled to receive a shot of the Adimmune H1N1 vaccine on its first day on the market.

    The success of the vaccine production program marks a breakthrough in Taiwan's biopharmaceutical technology development.

    Situated at the start of a winding country road surrounded by rice paddies, Adimmune's vaccine factory does not quite fit with the idea that a high-tech vaccine production facility should be housed in a carefully designed biotech industrial park. On the contrary, the factory is an obscure structure hidden behind a strikingly decorated Taoist temple.

    Its unimpressive outlook, however, in no way diminishes its outstanding achievement as Taiwan's first and the world's 12th swine flu vaccine production facility.

    As part of a massive H1N1 immunization program amid the global outbreak, the government has ordered 10 million doses of Adimmune's vaccine, in addition to procuring 5 million doses from the multinational pharmaceutical supplier Novartis. The immunization program kicked off Nov.1, with Typhoon Morakot survivors and health care personnel getting shots first in line.

    When Adimmune announced its H1N1 vaccine development program in May, it met stiff resistance, with some health care professionals even saying outright that they would boycott the local product.

    Adimmune Chairman Chan Chi-hsien, a former DOH minister, expressed full confidence in his company's ability, however, and gave an assurance that if his company's vaccine did not meet international standards, production would be halted completely and the vaccine would not enter the market.

    With its production facility passing certification and the vaccine completing human clinical trials, doubts and criticisms were gradually replaced by praise and affirmation. Last week, the vaccine finally received DOH marketing certification.

    Ma's decision to get a shot of Adimmune vaccine is expected to give more endorsement to the product, now being billed as yet another "pride of Taiwan." Chen Chien-jen, an Academia Sinica academician who has also served as DOH minister, said the vaccine's success is an important achievement because epidemic control forms an integral part of national security.

    "It is admirable and enviable that half of Taiwan's population will be able to be immunized against swine flu while some other countries are facing vaccine shortages, " Chen said, adding that Adimmune's success can also help fuel domestic biopharmaceutical development.

    Huang Li-ming, director of National Taiwan University Hospital's pediatric infectious disease department, admitted that between 10 percent and 20 percent of local parents remain doubtful about the safety and effectiveness of the locally produced H1N1 vaccine.

    "In recent weeks, I have often been grilled during outpatient clinics as to whether Adimmune vaccine is safe or which one -- the locally produced one or the Novartis vaccine -- is better, " Huang said.

    Huang, who presided over the Adimmune clinical trial program, said the vaccine is on a par with its foreign counterparts in terms of both safety and efficacy.

    "Apprehensive or jittery parents tend to become more confident of the local vaccine after listening to my explanation," Huang said.

    Chou Chih-hau, deputy director of the DOH's Centers for Disease Control, said about 3 million local people on the priority list for immunization will be administered with the Adimmune vaccine.

    Previously, Adimmune's only experience with flu vaccine was packaging seasonal flu vaccine produced by Japan's Kitasato medical research center.

    In manufacturing the H1N1 vaccine, the company started from scratch and succeeded in developing a world-class product in less than six months.

    With an annual production capacity of 30 million doses, Chan said, the company is seeking to export its products. Moreover, the company plans to sell its original vaccine to Europe through the Dutch company Crucell, one of its shareholders.

    Adimmune has come a long way to emerge as Taiwan's only human vaccine producer.

    When the government decided to develop and produce SARS and H5N1 bird flu vaccines under a build-operate-own (BOO) formula in 2003, Adimmune lost to a foreign competitor in a bid to secure the NT$4 billion contract.

    The company then decided to go its own way and built a vaccine plant in partnership with Crucell in 2007.

    The government-backed BOO project later fell through when the foreign contractor merged with another business group.

    After years of delay, the government finally abandoned the BOO project and decided to give an opportunity to Adimmune by guaranteeing to procure its vaccines under contract.

    When Chan took over as Adimmune chairman last year, the company was still heavily in debt following the NT$3 billion expenditure for the vaccine factory in which the company had invested NT$700 million.

    Under Chan's leadership, however, the company managed to secure investment from the government-owned National Development Fund, which now has a roughly 20 percent or so stake in the company.

    In addition to financial support, the DOH has also posted specialists in the plant to offer technological assistance, even though the company remains a privately own business.

    During his tenure as DOH minister between 1997 and 2000, Chan initiated a publicly funded seasonal flu vaccination program, so it is fitting that Taiwan has successfully produced its own swine flu vaccine under his supervision.

    Under Chan's leadership, Adimmune will not be satisfied with just serving the local market. Chan, a U.S.-trained surgeon, said in an interview with CNA that his company plans to set up a second vaccine factory to produce vaccines for other diseases and even innovative ones, such as an enterovirus vaccine and a dengue fever vaccine.

    "We have a dream of becoming one of the major vaccine manufacturers in the world, " Chan said. "With hard work, we believe it is not an impossible dream." (With reporting by Chen Ching-fang)

    www.etaiwannews.com/etn/news_content....
  5. forum rang 4 harvester 16 november 2009 21:54
    quote:

    aossa schreef:

    Taiwan scores biotech breakthrough with H1N1 vaccine success

    With an annual production capacity of 30 million doses, Chan said, the company is seeking to export its products. Moreover, the company plans to sell its original vaccine to Europe through the Dutch company Crucell, one of its shareholders.

    When the government decided to develop and produce SARS and H5N1 bird flu vaccines under a build-operate-own (BOO) formula in 2003, Adimmune lost to a foreign competitor in a bid to secure the NT$4 billion contract.

    The company then decided to go its own way and built a vaccine plant in partnership with Crucell in 2007.

    The government-backed BOO project later fell through when the foreign contractor merged with another business group.

    After years of delay, the government finally abandoned the BOO project and decided to give an opportunity to Adimmune by guaranteeing to procure its vaccines under contract.

    When Chan took over as Adimmune chairman last year, the company was still heavily in debt following the NT$3 billion expenditure for the vaccine factory in which the company had invested NT$700 million.

    Under Chan's leadership, however, the company managed to secure investment from the government-owned National Development Fund, which now has a roughly 20 percent or so stake in the company.

    Under Chan's leadership, Adimmune will not be satisfied with just serving the local market. Chan, a U.S.-trained surgeon, said in an interview with CNA that his company plans to set up a second vaccine factory to produce vaccines for other diseases and even innovative ones, such as an enterovirus vaccine and a dengue fever vaccine.

    "We have a dream of becoming one of the major vaccine manufacturers in the world, " Chan said. "With hard work, we believe it is not an impossible dream." (With reporting by Chen Ching-fang)

    www.etaiwannews.com/etn/news_content....
    Interessante passages.
    Crucell gaat zo lijkt het nu goed garen spinnen met haar belang in Adimmune en het commerciële (export) contact.
  6. [verwijderd] 20 december 2009 21:21
    More Filipinos can access A(H1N1) vaccine

    This month, shipments of the Adimmune vaccine, globally distributed by vaccine manufacturer Crucell, will be exclusively handed to the Philippine government by Glovax Philippines.

    The Philippines recently received a donation of nine million doses of A(H1N1) vaccine from the World Health Organization (WHO). In a statement, Health Secretary Francisco Duque 3rd said that the Department of Health is still exerting its best effort to procure its own P100-million worth of vaccines from leading vaccine companies.
    Glovax Inc., an international dealer of vaccines focused on regional population needs, saw the world shortage of vaccine supply and in turn already pre-ordered and secured 100,000 doses of A(H1N1) swine flu vaccines from Adimmune for the Philippines. This month, shipments of the Adimmune vaccine, globally distributed by vaccine manufacturer Crucell, will be exclusively handed to the Philippine government by Glovax Philippines.

    Glovax Philippines President Giovanni Alingog said that Glovax Inc., aims to help the government provide the needed vaccine supply for the 97 million Filipinos. He explained that the additional supply will complement government’s efforts to keep the Philippines A(H1N1) free, using massive education efforts, school-to-school temperature readings, hand washing campaigns, strict travel quarantine measures and immunization plans.

    Alingog reiterated that the vaccine, upon arrival, can be requested from private physicians, and will be administered on a first-come-first-served basis. Individuals can already reserve a shot through their doctors or thru vaccination clinics such as VAXCEN.

    Vaccination is being recommended for health workers who are at the front line of health services, travelers, overseas workers, athletes who would compete in international games, pregnant women and other immuno-compromised individuals such as the elderly and young children.

    Alingog noted that in China, 70 million Chinese have already been vaccinated with a rate of 1.5 million immunizations daily.

    In Taiwan, President Ma Ying-jeou led the vaccination drive against A(H1N1) at an elementary school in Taipei in late October and even received a shot, accompanied by celebrities who were vaccinated along with pregnant women, elementary school children, younger infants and gravely ill patients.

    In the US, presidential daughters Malia, 11 and Sasha, 8 were vaccinated when it became available for Washington, D.C. schoolchildren, underscoring how safe President Barack Obama considers the A(H1N1) vaccine to be. Australia has also embarked on the biggest vaccination program in its history, offering free swine flu vaccine to every person in the country.

    Widespread H1N1 vaccine programs rolled out from coast to coast in Canada last month, where people lined up for shots in clinics in 10 provinces and two territories, as part of the largest immunization campaign in the country.

    Similar anti A(H1N1) vaccination measures are being undertaken in over 40 countries across the globe.
    www.manilatimes.net/index.php/sunday-...
  7. forum rang 4 aossa 27 december 2009 21:04
    Major Products
    (1) JEV vaccine, domestic market share : 100%
    (2) Tuberculin PPD, domestic market share : 100%
    (3) Tetanus toxoid, domestic market share : 50%
    (4) Influenza vaccine, domestic market share : 30%

    Current Facility Production Capacity
    (1) JEV vaccine:1.5 million doses
    (2) Tetanus toxoid:2.5 million doses
    (3) Influenza vaccine:30 million doses
    (4) A (H1N1) vaccine:100 million doses

    www.adimmune.com.tw/eng/about.php?act...
  8. maxen 5 januari 2010 00:27
    Van Perseazes, IV:

    Lawmakers to increase pay for vaccine deaths
    ARROGANT: Lawmakers called for the president and trustees of Adimmune to attend a meeting. However, officials from the A(H1N1) vaccine maker failed to show
    By Shelley Shan
    STAFF REPORTER
    Friday, Jan 01, 2010, Page 4
    Lawmakers serving the legislature’s Social Welfare and Environmental Hygiene Committee yesterday proposed raising the compensation for deaths caused by the A(H1N1) vaccine.

    The Centers for Disease Control (CDC) announced on Tuesday that it was planning to increase the death compensation from NT$2 million (US$62,500) to NT$6 million.

    However, legislators from the Chinese Nationalist Party (KMT) and the Democratic Progressive Party (DPP) said they wanted the stated amount increased in light of a series of cases in which patients developed a negative reaction to the vaccines. One of the cases involved a seven-year-old boy surnamed Liu (劉), who died a month after he was vaccinated.

    The version proposed by KMT Legislator Hou Tsai-feng (侯彩鳳) called for raising the death compensation from NT$6 million to NT$10 million, while DPP Legislator Chen Chiech-ju’s (陳節如) version would double the CDC’s proposed compensation to NT$12 million.

    The Department of Health (DOH) will consider both proposals before it makes its final decision.

    The DOH was scheduled to brief lawmakers at the committee yesterday about how the department executed its immunization plans and handled negative reactions to the vaccines. The committee also invited Adimmune Corp (國光生技) president Steve Chan (詹啟賢) and the company’s trustees to attend the meeting, but none showed up.

    The absence of Adimmune’s representatives upset legislators because the company’s vaccines had been shown to lead to side effects in patients and sometimes deaths. Legislators accused DOH Minister Yaung Chih-liang (楊志良) of being powerless over the company, even though it is 30 percent government owned. Some legislators said that trustee Oliver Hu (胡幼圃) was also a member of the Examination Yuan and proposed his replacement.
    www.taipeitimes.com/News/taiwan/archi...
    ********************
    Taiwan gives H1N1 vaccine choice to public

    TAIPEI (Taiwan News) – Members of the public can choose whether they are immunized with Taiwanese or with imported vaccines against the A (H1N1) swine flu virus, Department of Health Minister Yaung Chih-liang said Monday.
    The announcement followed public doubts about the Taiwanese shots, made by Adimmune Corporation, after the estimated deaths of seven people after their vaccinations.
    The death of a seven-year-old boy in Taichung last month and alleged other deaths as well as miscarriages caused a drop in the number of people willing to receive the shots.
    While vouching for the safety of the local product, Yaung said members of the public would be allowed to choose between the Adimmune vaccine and its competitor from Swiss pharmaceuticals giant Novartis.
    He made the concession after a request from several visiting lawmakers, including opposition Democratic Progressive Party member Chen Ying, reports said. The minister said preparatory work would take a few days, after which the choice would become possible.
    Officials said more than 1.5 million doses of Novartis were still available, but they predicted complains from residents of locations where only one kind of vaccine was available.
    Adimmune took out advertisements in major newspapers Monday to defend the safety of its vaccines. The number of patients being hospitalized and of schools closing down because of A (H1N1) outbreaks had gone down since the immunizations began, the ad said.
    The company’s vice president Simon Kao said the number of problem cases in Taiwan was lower than in the United States and Europe.
    “We are a very serious company, not worse than foreign companies,” he said.
    Instead of publishing ads, the company should hold an official news conference and send its chairman to the Legislative Yuan for questioning, said Chang Yao-chung, the opposition Democratic Progressive Party member of the Taichung City Council who acted on behalf of the dead boy’s parents.
    Adimmune Chairman Steve Chan is known as a confidant of President Ma Ying-jeou as he played a key role in his election campaign in 2008.
    The DOH announced Monday that so far about 5 million people had been vaccinated, or less a quarter of the total population. A total of seven people had died after being vaccinated, Yaung said, though the DOH has always denied the deaths were directly linked to the shots.
    A 25-year-old became the ninth pregnant woman to be hospitalized with A (H1N1), the CDC announced Monday. She lost her child after taking the anti-flu drug Tamiflu, but had not been immunized, the CDC said.
    The government took its immunization campaign to its own offices Monday, with hundreds of employees at the Executive Yuan lining up for the shots. One of the volunteers, government spokesman Su Jun-pin, said Premier Wu Den-yih and Vice Premier Eric Liluan Chu had received their shots last year, at the beginning of the campaign.
    Out of the Yuan’s 600 staff members, about 400 did not want the Adimmune vaccinations, cable station Sanlih E-TV reported Monday.
    The DOH also decided to establish a commission to review the contested cases of immunization victims. Members will include seven representatives from outside the medical sector, including consumers and parents organizations.
    www.etaiwannews.com/etn/news_content....
  9. maxen 7 januari 2010 13:55
    quote:

    maxen schreef:

    ...
    The committee also invited Adimmune Corp (國光生技) president Steve Chan (詹啟賢) and the company’s trustees to attend the meeting, but none showed up.

    The absence of Adimmune’s representatives upset legislators because the company’s vaccines had been shown to lead to side effects in patients and sometimes deaths.
    ...
    Ron, we could use some legitimate bashing here...
    can't you find anything about Steve Chan's hair?
    Steve and Ronald being palls? Anything!
  10. forum rang 4 aossa 7 januari 2010 14:04
    Taiwan to give public choice of H1N1 vaccines from Saturday

    Taiwan News, Staff Writer
    2010-01-06 07:23 PM

    TAIPEI (Taiwan News) – Members of the public will have the choice between locally made A (H1N1) flu vaccines from Adimmune Corporation and imported doses from Switzerland’s Novartis beginning this Saturday January 9, Centers for Disease Control Director-General Steve Kuo announced after a meeting with local health officials.

    Several deaths have occurred after vaccinations, provoking questions over the safety of the local vaccine made by Adimmune Corporation and a drop in the number of people willing to take part in the government’s immunization campaign.

    About 70 percent of clinics and hospitals already had both brands, but the authorities would step up the distribution to the other locations until it reached a level of 95 percent out of 3,000 vaccination points, Kuo said.

    Schools however would continue to use the Adimmune vaccines only, he said.

    He allayed fears that the country would run out of the vaccines. Taiwan had 1.89 million doses of Novartis and 1.69 million of Adimmune available, he said. The CDC chief did admit that on the contrary, there might be a surplus of the vaccines. The contracts did not include the right to send excess vaccines back to the suppliers, Kuo told lawmakers.

    The CDC also published the level of problem cases for each brand. Adimmune registered side effects or complications for 8.7 percent out of 100,000 doses, but Novartis had a higher rate of 13.2 percent.

    Mixing vaccines from the two brands was possible, though for children under nine years of age, parents would have to sign a release form to bear responsibility for any side effects.

    The CDC said a total of 400 cases were known where the first and second immunizations used vaccines from different suppliers, but none of the cases had resulted in problems for the patients.

    The harsh criticism of the health authorities over their handling of the flu virus forced Department of Health Minister Yaung Chih-liang to break out in tears Wednesday during questioning by legislators.

    Yaung took out his handkerchief and wiped his eyes while listening to words of encouragement from ruling Kuomintang lawmaker Kuo Su-chun.

    Yaung denied allegations made in a radio interview by Adimmune Chairman Steve Chan Tuesday that the DOH tried to block the company from releasing information about the vaccine because it would violate restrictions on the advertising of medical services and products.

    Chan accused the DOH of being partly responsible for the current credibility problem because it cautioned him against holding a news conference about the vaccine, and then called his company to remove information from its web site.

    Yaung said there was a ban on publishing data before tests on humans were completed, but once that phase was over, the company could do with its information what it wanted.

    Within the opposition Democratic Progressive Party, lawmaker Twu Shiing-jer became a target of criticism Wednesday for apparently changing his stance on the vaccines, reports said.

    Twu, a former DOH minister, appeared on television Tuesday evening promoting vaccinations against the flu virus. Yet, earlier that day, Chan had accused him in a radio interview of saying his company’s vaccine was the worst in the world.

    Twu defended his appearance in a series of pre-recorded public interest spots by pointing out he was not advertising the Taiwanese-made vaccine.

    “I encourage everyone to get immunized but I do not promote the Adimmune vaccine,” Twu told reporters.
  11. flosz 12 januari 2010 10:09
    Ex-health minister TV spots to be footnoted
    TAIPEI, Taiwan -- Pro-vaccine commercials featuring an outspoken critic of the current administration will continue to run, but instead appended with a footnote, health authorities said yesterday.
    Democratic Progressive Party (DPP) legislator Twu Shiing-jer, a former health minister, had asked health officials during an impromptu press conference to pull TV spots spotlighting the politician encouraging residents to get immunized against the A(H1N1) flu virus, said the United Evening News.
    The Centers for Disease Control (CDC) affirmed that a newer version of the ad will bear a brief explanation of Twu's stance, which the lawmaker said is to solely lend backing to the immunization program, not to endorse local vaccine manufacturer Adimmune Corp.
    CDC Deputy Director-General Shih Wen-yi said Twu's role as a CDC ambassador is one of pro-bono capacity and simply to help champion vaccination efforts amid dampened public reception of the vaccine.
    Twu was approached by health authorities because of his public health expertise and support for the current immunization policy, noted Shih.
    The lawmaker had famously referred to the local A(H1N1) vaccine as the “world's worst vaccine,” but was most recently hounded by peers across the aisle for the about-face stamp of approval by starring in a vaccine commercial, said the Broadcasting Corporation of China (BCC) news.
    www.chinapost.com.tw/taiwan/national/...
    ************
    Death of boy who died after receiving H1N1 shot attributed to DIC
    Taipei, Jan. 9 (CNA) A preliminary autopsy on a boy who died several weeks after being vaccinated against the H1N1 has concluded that a pathological activation of blood clotting mechanisms -- called disseminated intravascular coagulation (DIC) -- caused his death.
    The Taichung District Prosecutors' Office made the conclusion public Saturday.
    "DIC caused bleeding in the brainstem (the lower part of the brain), resulting in the boy's death," the office said.
    The final results of the autopsy will be determined after a further study of the boy's immune system tissues is conducted, the office added.
    Centers for Disease Control (CDC) Deputy Director-General Shih Wen-yi said he respects the judiciary's conclusion.
    Asked about the connection between DIC and the H1N1 vaccine, Shih said that for now, he could only say that the possibility of the vaccine causing DIC is "very, very low." The 7-year-old child, who lived in central Taiwan, died on Dec.
    21, several weeks after being vaccinated against the H1N1 flu virus.
    His father, a physician, has since blamed the vaccine for the death of his only son.
    The highly publicized case has spread fears over the safety of the vaccine and frustrated the progress of the government's national immunization program, which began Nov. 1 amid a worldwide outbreak.
    The immunization drive has also slowed down in part because of worries over the safety of the vaccine produced by local pharmaceutical company Adimmune Corp., and the Cabinet-level Department of Health (DOH) responded by allowing people to choose between the Adimmune vaccine and that produced by Swiss-based Novartis.
    The DOH hoped the choice would boost the immunization rate, but not as many people showed up for shots on the first day of the new measure as had been expected, according to Shih.
    In Taipei City, only 33 adults and six children received shots of the Novartis vaccine at Taipei Veterans General Hospital during the day, while 13 adults and 24 children received the Adimmune vaccine, Shih said.
    Shih repeated his call for people to be immunized, saying that if one gets the shot before Jan. 23, one can be safe from a flu attack during the Chinese New Year holiday in February, which is when the H1N1 outbreak is expected to hit its peak.
    www.etaiwannews.com/etn/news_content....
  12. maxen 12 januari 2010 10:40
    Terecht of niet, de vermeende doden en bijwerkingen door 't H1N1 vaccin van AdImmune is slecht voor de reputatie van AdImmune.
    Wellicht zal het ook z'n uitwerking hebben op de verkoop van vaccins voor gewone griep.
    Imagoschade komt te paard en gaat te voet.

    Nu is juist Crucell's Inflexal een hoger in het segment liggend vaccin, met als belangrijk marketing element hoge puurheid en minder adjuvant en geen thiomersal (kwik), zodat het minder bijwerkingen zou vertonen. Zoals Crucell zelf zegt:

    "Inflexal® V was originally introduced in 1997, is registered in 43 countries and has extensive market experience, with more than 40 million doses confirming its safety profile. The tolerability of Inflexal® V is excellent due to its biocompatibility and purity"

    Er zullen dan toch enige kriebels ontstaan in Leiden en Bern, met betrekking tot
    1) distribiteurschap van Crucell voor Adimmune's H1N1 vaccin, en
    2) afname van flu antigen van AdImmune voor verwerking in Inflexal.

  13. flosz 19 januari 2010 10:18
    Vaccine producer sues critic for alleged defamation

    Adimmune Corp., the sole A(H1N1) flu vaccine producer in Taiwan, filed a defamation lawsuit Thursday against a critic who branded its vaccines unsafe.
    In a motion to defend its reputation, Adimmune's Vice President Simon Kao filed the suit with the Taipei District Court, requesting an apology and damage of NT$3 million from the man called Chun-hsu James Chen.
    Kao told journalists outside the court that Chen tarnished his company's image by claiming in his blog and in interviews with cable television stations that Adimmune's flu vaccine contains 50 times more organic mercury - a chemical ingredient - than similar vaccines produced overseas, and it holds formalin, another chemical ingredient, which should not be present.
    "A majority of H1N1 flu vaccines in the world uses formalin to render viruses inactive, and use organic mercury to inhibit the growth of bacteria," Kao said.
    "The traces of the two chemicals in Adimmune's H1N1 vaccine are within the international limits and are harmless to people." he said
    www.etaiwannews.com/etn/news_content....

    Time for Adimmune to show data
    www.taipeitimes.com/News/editorials/a...
  14. MeawandMoo1 28 januari 2010 20:02
    Ontwikkelingen bij Adimmune?

    www.adimmune.com.tw/eng/coming.php?no=7

    Onder het kopje "Upcoming"
    Entrovirus 71 vaccine

    Enterovirus 71 had particularly high pathogenic strength. It often caused the child under the age of five to have more serious complications in Taiwan every year, and the mortality was 1/10000 to 1/100000. Therefore, Enterovirus 71 has been considered an important emerging infectious virus. Since no effective anti-viral agent was found so far, to research and develop an Enterovirus 71 vaccine has already became common consensus of the domestic public health circle.

    Adimmune Corporation successfully developed serum-free cell culture technology for mass production of Enterovirus 71 vaccine through cell with in house serum-free culture medium. We hoped to build up a mass production process with high space utilization ratio, low manpower requirements, and stable performance. At the same time, a best mouse infection mode has been successfully established through the cooperation with academic communities. In order to enhance the mass production process and the quality of Enterovirus 71 vaccine, we were actively putting efforts into researching the best adjuvant prescription, administration routes, analytical methods, and the final specifications of Enterovirus 71 vaccine.
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