Kleintje66 schreef op 25 augustus 2021 22:29:
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Wetenschap is wat anders dan een verzameling onderzoeken waarin soms de uitkomst is dat het een positief effect kan hebben. Er zijn ook slechte onderzoeken op vele gebieden uitgevoerd bijv. doordat niet goed random werd toegepast. Om te zeggen dat het "soms werkt" heb je dus bewijs nodig en niet wat onderzoeken met een (positieve) uitkomst.
www.bhf.org.uk/informationsupport/hea...Ongoing research
Since those initial studies, there have been dozens of studies worldwide involving people with Covid-19 infection being treated with hydroxychloroquine.
Randomised controlled trials can provide the most robust information on the relative risks and benefits of taking the drug.
All of the evidence from trials of hydroxychloroquine to date is not supportive for a role for this drug against Covid-19. In the UK, the team behind the RECOVERY trial (a large trial testing a variety of treatments in people hospitalised with Covid-19) announced in June 2020 preliminary results showing that there was no benefit for people receiving hydroxychloroquine. Similarly, the World Health Organization's SOLIDARITY trial results showed that hydroxychloroquine had no effect on survival, or on whether a person needed to be ventilated, or length of recovery, in people in hospital with Covid-19.
Studies have also looked into whether hydroxychloroquine could help people who are at an earlier stage of Covid-19 illness, or who are not ill enough to need hospitalisation. Again, the evidence so far doesn't support this. A trial in the US and Canada showed that taking hydroxychloroquine could not prevent people who were recently exposed to someone with Covid-19 from getting ill. In December 2020, another study where hydroxychloroquine (with or without azithromycin) was given to people with mild or symptom-free Covid-19 showed that did not reduce the number of people testing positive for the virus after six days.
Results from further trials will give us a fuller picture of whether there are specific groups of people who may benefit from taking hydroxychloroquine to help treat or prevent Covid-19. For example, the UK-led COPCOV trial is looking at whether taking hydroxychloroquine can help protect healthcare workers from getting Covid-19.