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MEI Pharma Inc (NASDAQ:MEIP)
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MEI Pharma: Upcoming Catalysts Will Drive Stock Rebound. seekingalpha.com/article/3024216-mei-... 52 week 1.69 - 12.23
Ook ingestapt op 1,95. Buitenkansje. Te hard afgestraft bij laatste resultaat. Lage rsi, meer in kas dan t aandeel momenteel waard is en een trigger half juni. Een koers van 3 dollar moet haalbaar zijn voor die tijd. Wel speculatief natuurlijk. De needham conferentie van vandaag heeft zo te zien al geleid tot meer positivo's in dit aandeel.
Gaat lekker weer vandaag. Staat op punt uitbreken 2,20-2,23 zone. Daarna weg open naar 3 dollar. Hoog volume
Schitterende stijging. Duidelijke doorbraak met oude weerstand. IJzersterk slot. Op hoogste punt (2,39) dag uit. Nu ligt er ruimte (gap) tot ongeveer 3,45. Ik blijf nog even zitten;) nog meer liefhebbers?;)
[quote alias=jan78 id=8424985 date=201504202217] Schitterende stijging. Duidelijke doorbraak met oude weerstand. IJzersterk slot. Op hoogste punt (2,39) dag uit. Nu ligt er ruimte (gap) tot ongeveer 3,45. Ik blijf nog even zitten;) nog meer liefhebbers?;) [/quote Yep, ik! Afgelopen vrijdag ingestapt. Wanneer ga je verkopen? Heb de helft op verkoop 3'dollar geplaatst.
Ik zit er in vanaf 2 dollar. Op 11 juni worden er belangrijke resultaten verwacht. Ik denk dat de koers voor die tijd de 3,50 heeft aangetikt. Misschien hoger. Maar spring er wel voor 11 juni uit, want ik gok daar niet op, want dan kan t ook mis gaan. Wel op t sentiment, die was overdeven negatief (zeer lage rsi). Vandaag een stapje terug, maar binnen de consolidatie. Daarna richting de 3 dollar
Goedemorgen, Begrijp me niet ,maar ze hebben toch slechts phase 2 studies,en die zijn toch juist mislukt?dan blijft er toch weinig over?dan kan men wel geld hebben,Mara dat is in dot geval toch ondergeschikt? Gr ber
Ze hebben meer in de pijpleiding dan alleen maar die slechte phase 2 resultaten
Nog genoeg potentieel voor een mooie rit op korte termijn.
Eisbear schreef op 22 april 2015 12:43 :
Ze hebben meer in de pijpleiding dan alleen maar die slechte phase 2 resultaten
Wat dan? Gr ber
Mooi herstel vandaag. Zal nog wel een bumpy flight worden tot half juni. Komt goed
Zijn er nog mensen die in cldx,arry, gern,ino, etc beleggen?
sl2722 schreef op 26 april 2015 12:50 :
Zijn er nog mensen die in cldx,arry, gern,ino, etc beleggen?
Sinds gisteren een positie in CLDX
sl2722 schreef op 26 april 2015 12:50 :
Zijn er nog mensen die in cldx,arry, gern,ino, etc beleggen?
Gaat lekker denk . echt brutal de laatste dagen , nu nog offering ino
Geduld, hoe dichter bij 11 juni, des te meer up
Goed nieuws! News Release Issued: May 4, 2015 (6:00am PDT) To view this release online and get more information about MEI Pharma, Inc. visit: investor.meipharma.com/index.php?s=43... MEI Pharma's Mitochondrial Inhibitor ME-344 Shows Enhanced Anti-Tumor Activity in Combination with Tyrosine-Kinase Inhibitor in Pre-Clinical Studies New Studies Identify Molecular Target, Mitochondria-Specific Effects of ME-344; Results from First-in-Human Clinical Study Published in Cancer Photos(1) SAN DIEGO, May 4, 2015 /PRNewswire/ -- MEI Pharma, Inc. (Nasdaq: MEIP), an oncology company focused on the clinical development of novel therapies for cancer, today announced new pre-clinical data showing mitochondria-specific effects of the Company's investigational drug candidate ME-344 in cancer cells, including significantly enhanced anti-tumor activity when combined with a tyrosine-kinase inhibitor (TKI). In addition, a recently published study found ME-344 to be a potent inhibitor of mitochondrial oxidative phosphorylation (OXPHOS) complex I, a direct molecular target. Logo - photos.prnewswire.com/prnh/20140805/1... "We continue to be very excited by the potential of this novel mitochondrial inhibitor," said Daniel P. Gold, Ph.D., President and Chief Executive Officer of MEI Pharma. "ME-344 has demonstrated broad and potent anti-tumor activity in a number of pre-clinical studies, followed by promising single-agent activity in the clinic. Now a body of data is emerging that show compelling anti-cancer effects when combining ME-344 with anti-angiogenic agents, such as TKIs, to inhibit both mitochondrial and glycolytic metabolism. These new data will help to direct future studies of ME-344 as we near completion of our Phase Ib study in small cell lung and ovarian cancers." In a paper published in the most recent issue of American Journal of Cancer Research1, the Company's collaborators at the MIMR-PHI Institute of Medical Research in Melbourne identified mitochondrial OXPHOS complex I as a direct molecular target of ME-344, its inhibition causing an immediate reduction of mitochondrial oxygen consumption. This important finding provides new understanding of how ME-344 induces cell death by disrupting mitochondrial metabolism. A copy of the paper is available at www.meipharma.com. To gain further insight into its mechanism of action, researchers at the Medical University of South Carolina in Charleston compared the activity of ME-344 in sensitive and naturally resistant lung cancer cell lines. In a dose dependent manner, ME-344 caused instantaneous and pronounced inhibition of oxygen consumption rates in drug-sensitive lung cancer cells, but significantly less in drug-resistant cells. Notably, drug resistance correlated with higher glycolytic metabolism in these cells. Using a well-characterized spontaneous breast tumor model, researchers at the Spanish National Cancer Research Centre in Madrid found that chronic treatment with the small molecule TKI nintedanib (formerly BIBF 1120) significantly diminished tumor cell glycolysis, however the growing tumor shifted to reliance on mitochondrial metabolism as its primary energy source. Subsequently, tumors primed by treatment with nintedanib showed significantly enhanced sensitivity to the mitochondrial inhibitor ME-344, with synergistic anti-tumor activity. These findings are presented in a poster, entitled "ME-344, a novel isoflavone with activity as a mitochondrial oxygenase inhibitor," which is available at www.meipharma.com. An abstract of the presentation can be found on the American Association for Cancer Research (AACR) website at aacr.org.
Verkocht vandaag, resultaten vallen tegen. Vol in IMNP gestapt!
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