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Wat is de waarde van uniQure?

7.806 Posts
Pagina: «« 1 ... 260 261 262 263 264 ... 391 »» | Laatste | Omlaag ↓
  1. ch@rter 5 december 2016 19:54
    Gbola Amusa of Chardan Capital said although the AAV-based gene therapy (GT) of Uniqure NV (NASDAQ: QURE has better timing, Spark Therapeutics Inc (NASDAQ: ONCE)has better efficacy in hemophilia B patients.

    Amusa gave the above comments after both companies presented their data at The American Society of Hematology (ASH) meeting on Saturday and Sunday.

    Conference Reveals
    “High-dose cohort data may not return uniQure to a competitive position in hemB GT,” Amusa wrote in a note.

    UniQure may have a first-mover advantage in hemophilia B AAV GT space, but Amusa noted that the “combination of modest FIX production and a liver enzymes profile that must be further elucidated raise significant concerns for the long-term potential for AMT-060 in the hemophilia space.”

    On the other hand, Spark Therapeutics showed better efficacy in hemophilia B gene therapy, but risks abound. The analyst continues to be impressed by the FIX activity of 12–65 percent achieved so far.

    Analyst's Take
    One key risk Amusa cited was the occurrence of two independent immune responses against the Spark100 capsid, which fundamentally undermines the hypothesis (lowering viral dose can evade immune activation against AAV GT).

    “We thus wonder how such immune evaluation will be performed in pivotal trials or in the real world,” Amusa highlighted.

    He posited whether the immune monitoring should be limited to the first 12 weeks, which is believed to be the key period for immune response against AAV. He also questioned whether future use requires rapid steroid treatment upon liver enzyme elevations to maintain AAV function.

    Amusa has a Buy rating on uniQure and a Neutral rating on Spark Therapeutics.

    At last check after a significant early morning drop, uniQure shares were up 3.42 percent at $5.87. Spark shares were up 1.52 percent.
  2. forum rang 10 DeZwarteRidder 5 december 2016 23:52
    quote:

    DeZwarteRidder schreef op 2 december 2016 21:58:

    [...]
    CytoDyn Inc. (CYDY)

    Other OTC - Other OTC Delayed Price. Currency in USD
    In watchlist
    0,729+0,064 (+9,62%)
    As of December 2 3:37 PM EST. Market open.
    CytoDyn Inc. (CYDY)

    Other OTC - Other OTC Delayed Price. Currency in USD
    In watchlist
    0,795+0,066 (+9,05%)
    At close: 3:59 PM EST

    ====================================================

    voor het eerst getipt op 67 cent en vandaag ruim 19% hoger gesloten.
    Met dank aan Charlie Sheen....!!!
  3. forum rang 10 DeZwarteRidder 5 december 2016 23:54
    CytoDyn to Present at LD Micro Main Event on December 7
    GlobeNewswire•December 1, 2016

    VANCOUVER, Washington, Dec. 01, 2016 (GLOBE NEWSWIRE) -- CytoDyn Inc. (CYDY), a biotechnology company focused on the development of new monoclonal antibody therapies for combating human immunodeficiency virus (HIV) infection, announces that Nader Pourhassan, Ph.D., President and CEO, will present at the LD Micro Main Event on December 7, at 2:00 p.m. Pacific Time (5:00 p.m. Eastern Time). The conference is being held at the Luxe Sunset Hotel in Los Angeles.

    A live webcast of the presentation will be available on the Company’s website at www.cytodyn.com under the Investors section/IR Calendar or at wsw.com/webcast/ldmicro11/cydy and will be archived for 90 days. Web participants are encouraged to login to either website 15 minutes prior to the start of the webcast to register, download and install any necessary software.
  4. T. Montana 5 december 2016 23:58
    quote:

    flosz schreef op 5 december 2016 23:17:

    Djeezzzz

    Jefferies QURE HemBash16

    twitter.com/_b_i_o_t_e_c_h_/status/80...

    Volgens Wedbush enz. "QURE looks uncompetitive." Kennelijk kennen ze niet kijku (net zo min als QURE kan verkopen natuurlijk). Klinkt enorm oubollig en ik realiseer me dat je in de VS heel ver komt met hard te roepen dat je de beste bent, of "tremendous" zoals Trump pocht, maar ik hoop dat hier toch het ouderwetse motto eerlijkheid duurt het langst zegeviert. Pijplijn getrimd, het vizier op Hem B, geen enkele reden om niet als eerste de eindstreep te halen en vervolgens het grootste marktaandeel op te eisen. Spark heeft daar überhaupt beperkingen.
  5. vaste koers 6 december 2016 00:06
    Wat is wijsheid bij dit aandeel?
    Ik volg het al een tijd.
    Heb er ook een portie in bezit.
    En snap er niets van.
    Het aandeel is in anderhalf jaar gegaan van 8 naar 33 euro.
    En in de volgende anderhalf jaar van 33 naar 6 euro.
    Wie kan er opheldering geven?
    Anderhalf jaar blijven zitten en zijn we dan weer bij 33 euro?
    Of wordt het nooit meer dan 10 euro?
7.806 Posts
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