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Aandeel Pharming Group AEX:PHARM.NL, NL0010391025

  • 0,881 19 apr 2024 17:35
  • +0,013 (+1,50%) Dagrange 0,869 - 0,889
  • 8.926.686 Gem. (3M) 6,9M

Pharming februari 2019

9.435 Posts
Pagina: «« 1 ... 448 449 450 451 452 ... 472 »» | Laatste | Omlaag ↓
  1. [verwijderd] 28 februari 2019 13:01
    Transgenic Mammals Likely To Transform Drug-Making.
    ..
    Another area being pursued by researchers is the mass production of hemophiliac blood factors and other blood proteins. The American Red Cross set up an R&D transfusion biology lab about 10 years ago to help contain the growing problem of HIV contamination in the U.S. blood supply. "We were looking at what the future would be in terms of trying to replace some of the unsafe proteins," says Bill Drohan, senior director of plasma development at the American Red Cross's Holland Laboratory, the organization's research arm based in Rockville, Md. "We took two tacks: One [involved] ways of inactivating viruses in plasma and the other was trying to produce the proteins by recombinant technology."

    Drohan notes that blood proteins had been made this way in tissue culture, but this was more expensive than isolating them from plasma. "So we looked at other ways of making it, and that's what brought us into the production of proteins in the milk of transgenic animals."
  2. [verwijderd] 28 februari 2019 13:02
    quote:

    beeldscherm schreef op 28 februari 2019 13:01:

    Transgenic Mammals Likely To Transform Drug-Making.
    ..
    Another area being pursued by researchers is the mass production of hemophiliac blood factors and other blood proteins. The American Red Cross set up an R&D transfusion biology lab about 10 years ago to help contain the growing problem of HIV contamination in the U.S. blood supply. "We were looking at what the future would be in terms of trying to replace some of the unsafe proteins," says Bill Drohan, senior director of plasma development at the American Red Cross's Holland Laboratory, the organization's research arm based in Rockville, Md. "We took two tacks: One [involved] ways of inactivating viruses in plasma and the other was trying to produce the proteins by recombinant technology."

    Drohan notes that blood proteins had been made this way in tissue culture, but this was more expensive than isolating them from plasma. "So we looked at other ways of making it, and that's what brought us into the production of proteins in the milk of transgenic animals."
    Pharming BV is betting the farm, so to speak, on cows and rabbits for its transgenic products. The company was the first to produce transgenic cattle, reports Gerard van Beynum, Pharming's vice president of product development. Pharming BV has two main products, one made in cows and another in rabbits. Human lectoferrin, a protein that works as a natural antibiotic, is made in the milk of female offspring of Herman the bull, one of the first animals used in Pharming's transgenic program. "In fact, it's found in human milk," notes van Beynum. One potential application, he says, is as a neutraceutical, an infant formula additive to be used for immune-depressed babies or perhaps a product for older patients on chemo- or radiotherapy. Another use could be as a pharmaceutical during cardiac surgery to decrease operation-related infections. Preclinical trials have started for this product.
    At the end of this year, says van Beynum, Pharming expects to start clinical trials in Europe using human alpha glucosidase produced in rabbits to treat Pompe's disease. Patients with this lethal and incurable muscle disorder lack the enzyme alpha glucosidase. "This is our lead product," remarks van Beynum.

    Because there's no drug available for treating the disease, van Beynum expects the clinical trials and regulatory review to be hastened. He expects to get the enzyme commercialized by 1999: "We might have the first [transgenic] product on the market."

    kunnen we zeggen, history repeats ???
  3. Blèèhhh 28 februari 2019 13:04
    quote:

    voda schreef op 28 februari 2019 12:52:

    [...]
    Super voor je Mar. Ik zit ook nog maar een paar centen vandaan op break-even. Daarna kan het heel erg hard gaan!
    Lekker he! ik sta ook groen vanaf vanochtend (93.5 oid) heb 25 %verkocht op 96.7... puur om toekomstige fluctuaties weer op te vangen en weer wat risico te spreiden.. ik koop niet bij voor t onder de 80 ct staat en ga er van uit dat we daar niet meer komen
  4. [verwijderd] 28 februari 2019 13:06
    Calling fibrinogen the Red Cross's most economically important pursuit, Drohan states that "it could be used in bypass surgery grafts to help speed healing of the suture." The Red Cross has finished three preclinical studies with fibrinogen, and it's now in regulatory review at the Food and Drug Administration.
  5. Emmen2019 28 februari 2019 13:06
    Vanochtend maar even voorzichtig naar een Nieuwe Ford gekeken :-) maar zonder gekkigheid :-) er is echt iets gaande in mijn persoonlijke beleving , het begon vind ik met een 3 tal berichten die niet van Pharming zelf kwamen , daarna kwam vorige week de dag van de stijging en die loopt dus door deze week , niet langer 1 dag stijging en dan weer down nee het loopt door , zou het dan toch zijn dat partijen het stokje over geven bij het coveren op een bepaalde koers omdat dat ooit is afgesproken toen ze hun stukken kregen geleverd bij de stapsgewijze daling ?? niemand die het weet maar dat is helaas wel vaker zo op de beurs waar hele grote belangen spelen.

    Fijne dag nog allemaal en eind van de dag nog een kleine Freeze door de 1,000 zou feestelijk zijn :-)
9.435 Posts
Pagina: «« 1 ... 448 449 450 451 452 ... 472 »» | Laatste |Omhoog ↑

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