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bbc.com/news/health-40566761 dig this....:)))
dan wil je toch geen bloodproducts meer he
www.bbc.com/news/health-40566761 Is weer eens te meer duidelijk dat de bloedbanken nog voorzichtiger zullen moeten zijn en bloeddonoren nog beter moeten screenen en niet bloeddonoren moeten aantrekken tegen betaling en zeker niet zoals in GB gebeurde door gevangenen bloed af te laten staan. Natuurlijk komen zich dan ook bijv. zieke mensen melden of junkies die bloed doneren omdat ze het geld broodnodig hebben. Zie ook de documentaire op tv van een maandje geleden.
Wel tevreden schreef op 13 juli 2017 11:52 :
dan wil je toch geen bloodproducts meer he
Weet je, het erge van deze zaak is, dat je in ziekenhuizen afhankelijk bent van bloedproducten. Je moet erop kunnen vertrouwen dat gezond bloed is gebruikt. Hetzelfde met medicijnen. Een bloedvrij medicijn als Ruconest is daarom naar mijn mening altijd te verkiezen boven het bloedgerelateerde product. Bovendien wordt dan het steeds schaarser wordende gedoneerde bloed van gezonde mensen gebruikt waar het nodig is en voor medicijnen waar geen alternatief voor is. Bijna iedereen hier is wel eens geopereerd of gebruikt medicijnen. Artsen en patiënten moeten kunnen vertrouwen op het bloed(plasma) of medicijnen die ze gebruiken/voorschrijven.
Shire weet inmiddels dat het einde verhaal zal zijn binnenkort Waarom ,en zal dat eenmalig melden ,denken jullie dat FDA zolang bezig is met Pharming men wil10000% zekerheid hebben bloed gerelateerd gaat er helemaal uit. Er is niet eens voldoende gezond bloed om slachtoffers van ongelukken dan wel operatie's te bedienen. FDA neemt straks een zeer wel overwogen beslissing mmi. Ruud..
Pharming lees Sijmen de Vries & zitten in een zetel wacht nu maar af. het wordt de sensatie van het jaar zie Pharming aandeel 2017 ;-) Ruud..
waarom al die draadjes? Waarom leest u het forum niet door? Dit bericht heb ik reeds op 11 juli geplaatst in het draadje www.iex.nl/Forum/Topic/1133440/69/Sec... BoOOOming schreef op 11 juli 2017 15:34 :
Theresa May launches inquiry into contaminated blood scandal
www.independent.co.uk/news/uk/politic... extract:
Factor VIII was used to treat people with haemophilia because it helped their blood clot.
It was later discovered that much of the blood used to create the product was taken
from American prisoners who were paid for their blood.
Aangezien ik geen nieuw draadje wilde beginnen, mijn info daarom toegevoegd aan dit draadje. Aangezien ik denk dat de plasma tekorten in de toekomst groter gaan worden hierover wat info gezocht. Ik ben benieuwd of er op hoog niveau hierover gesproken wordt zodat in de toekomst regelgeving gaat komen om ervoor te zorgen dat daar waar het plasma het hardst nodig is ook terecht gaat komen. Wat dan betekend dat de medicijnen die op een alternatieve manier gemaakt kunnen worden voorgang krijgen op medicijnen die van plasma gemaakt worden. Nou ja eigenlijk dat het plasma eerst verstrekt wordt aan de instellingen die het het hardst nodig hebben. The big business of blood plasma The Lancet Haematology Published: October 2017 PlumX Metrics DOI: doi.org/10.1016/S2352-3026(17)30183-7 China, a country that holds the questionable honour of being a world leader in liver disease, is now also the highest consumer of serum albumin, using 300 tonnes annually, roughly half of the worldwide total use, according to an article in the Financial Times. Serum albumin is most commonly derived from blood plasma, and over half of the albumin in China is imported. This increasing demand is driving up prices, and fake products billed as albumin have been found. Liver disease is a growing problem in China, primarily because of the high burden of viral hepatitis in Asia, but also because of the growing prevalence of non-alcoholic fatty liver disease. Advanced stages of liver disease are characterised by protein wasting and can result in albumin depletion, which can have major effects on the cardiovascular system, renal system, and risk of infection. Human serum albumin is the most abundant protein found in the blood. It is a multifunctional non-glycosylated, negatively charged plasma protein that is synthesised primarily in the liver. Albumin regulates colloid oncotic pressure by its role in the intravascular protein pool, managing water retention, and via the Gibbs-Donnan effect. Albumin has long been used for various medical indications from trauma resuscitation to treatment of liver damage. Although there is conflicting evidence about just how useful human serum albumin is for certain liver indications, it is generally accepted as a useful treatment for those with liver damage. The proportion of individuals who donate blood in China is low, due to a myriad of reasons. In the 1990s, Henan Province had become a blood farm built on a criminalised plasma economy. Thousands of Chinese donors became infected with HIV and hepatitis C because of contaminated equipment. Although now disproven, the boasting of a young woman about her lavish lifestyle while working for the Red Cross Society of China had seriously damaged the reputation of the charity that helps the government collect blood. In 1998, China introduced a blood donation law banning the commercial sale of blood and encouraging voluntary donation instead. It also tightened rules on plasma collection and increased blood testing. However, Chinese law also limits individual whole-blood donations to twice a year, and provinces rarely share blood. Chinese law now encourages patients who require a blood transfusion to present a certificate showing that they, their friends or relatives, have donated blood when they need to access the national supply. For those who can afford it, they can overcome this requirement by accessing the black market in which mediators pay people off the street to donate blood at a state blood bank and sell their donation certificates to those who need them. Adding to the complexity of the issue is that there are two separate blood markets, one for whole blood and another for blood plasma. While whole-blood donations are primarily used for clinical transfusions, the plasma industry uses plasma to produce various blood products, including clotting factors, intravenous immunoglobulin, and albumin. Globally, the plasma industry is a big business. Companies that specialise in plasma have been regularly subjected to takeovers, and the industry is growing. It is generally accepted (and recommended by WHO) that the safest blood supplies are those freely given by carefully screened donors who have no vested interest. However, the model is different for plasma. Plasma donors are often paid and can donate much more frequently than whole-blood donors. Although most countries set a plasma donation limit of once every 2 weeks, in the USA, individuals are able to donate twice a week. The financial incentive can be appealing for those who struggle to raise funds by other means, which can encourage lying during medical screening and could adversely affect the health of the donors as well. With some companies pooling hundreds of thousands of donations together for processing, this can be an important safety risk. There have been suggestions that the USA use plasma to close the trade deficit between the USA and China. However, this economic relationship would need careful consideration and regulation to be viable on all sides. In view of the challenges of a safe and adequate supply of serum albumin from human blood, it is important to look for safe alternatives. Global efforts to eliminate viral hepatitis by 2030 will no doubt help to address the problem of liver disease in the future, and there are currently studies underway to produce human serum albumin from transgenic rice seeds. Prevention, alternative sources, and better regulation will hopefully enable the protection of the health of not only those who require human serum albumin, but also those who provide it.
Why you get paid to donate plasma but not blood By Elizabeth Preston January 22, 2016 www.statnews.com/2016/01/22/paid-plas... Donating plasma and donating blood are essentially the same process: the entry questionnaire, getting hooked up to a machine, the cookie afterward. But in the US there’s a key difference: one is an act of charity, and the other an act of commerce. So why is it that you get paid to donate plasma, but not blood? It’s a common misconception that the Food and Drug Administration bans paying for blood. In fact, it only says blood from paid donors has to be labeled that way. But hospitals won’t use it. In practice, nobody really pays for blood, said Mario Macis, an economist at the Johns Hopkins Carey Business School who has studied incentives for blood donation. “Even though it’s legal, it’s still considered not totally moral or ethical to pay cash to blood donors.” Aside from the ickiness of handing out literal blood money, the FDA worries that paying donors would jeopardize the safety of the blood supply. No one with a blood-borne illness is eligible to donate, but the agency worries that if money were on the line, donors might lie about their health or their risk behaviors. The science there is far from settled. But the World Health Organization finds it convincing enough that they discourage countries from paying blood donors. “Evidence shows significantly lower prevalence of transfusion-transmissible infections among voluntary nonremunerated donors than among other types of donors,” their commentary in 2013 read. Donated blood is tested for diseases, anyway, but the FDA says it intends those steps to be redundant security measures, “like layers of an onion.” Plasma donation — in which blood is drawn, plasma separated out, and then blood cells and other components put back into you — is often compensated. The FDA doesn’t require paid plasma donations to be labeled. The reason is that plasma collected this way never goes straight into another person. It’s broken into many different protein products that will become pharmaceuticals. Along the way, these components are processed to remove or kill any virus stowaways. “The risk of infection is inherently much lower,” said Dr. Christopher Stowell, who recently chaired the FDA’s Blood Products Advisory Committee. Whole red blood cells are too fragile to undergo the same kind of processing as plasma. And there’s some evidence that paying for plasma does, indeed, lead more people to conceal their disease status or risk behaviors. For instance, the Government Accountability Office looked at California’s blood versus plasma supply back in the 1990s and found that the plasma had much higher rates of HIV. There are reports of desperate donors lying about illnesses to donate for cash. However, the type of compensation matters. In a 2013 Science paper, Macis and others found that rewards such as gift cards, coupons, and T-shirts almost always boosted donations, and they didn’t find any effects on blood safety. (The FDA doesn’t count rewards like this as payment, as long as they can’t be easily turned into cash.) “Nonmonetary incentives do work,” Macis said. He thinks using more of these motivators could help the United States manage seasonal blood shortages. Were you hoping for more than a T-shirt? Don’t even think about selling a kidney. The National Organ Transplant Act of 1984 made it illegal to pay for organs. But in the 2011 case Flynn v. Holder, the US Court of Appeals for the Ninth Circuit ruled that a certain method of bone marrow donation could be compensated. Related Story: Blood from embryonic stem cells? Trials still years away Traditionally, bone marrow was collected in a surgical procedure, with a hollow needle stuck straight into the pelvis. But in a more common method called peripheral blood stem cell apheresis, donors take drugs that release the stem cells from their marrow into their blood. Then they donate the cells through a needle in the arm and an apheresis machine — just like a plasma donation. Centers that collect such cells pay up to $800, but they haven’t seen that much interest, the AP recently wrote. And the cells can’t be processed like plasma, so it’s unclear what the risk might be from paying donors in this nascent market.
Blood Facts and Statistics American red crosswww.redcrossblood.org/learn-about-blo... Every two seconds someone in the U.S. needs blood. Approximately 36,000 units of red blood cells are needed every day in the U.S. Nearly 7,000 units of platelets and 10,000 units of plasma are needed daily in the U.S. Nearly 21 million blood components are transfused each year in the U.S. The average red blood cell transfusion is approximately 3 pints. The blood type most often requested by hospitals is type O. The blood used in an emergency is already on the shelves before the event occurs. It is estimated that sickle cell disease affects 90,000 to 100,000 people in the U.S. About 1,000 babies are born with the disease each year. Sickle cell patients can require frequent blood transfusions throughout their lives. According to the American Cancer Society, more than 1.69 million people are expected to be diagnosed with cancer in 2017. Many of them will need blood, sometimes daily, during their chemotherapy treatment. A single car accident victim can require as many as 100 pints of blood. The number of whole blood and red blood cell units collected in the U.S. in a year: 13.6 million The number of blood donors in the U.S. in a year: 6.8 million Although an estimated 38 percent of the U.S. population is eligible to donate blood at any given time, less than 10 percent of that eligible population actually do each year. Blood cannot be manufactured – it can only come from generous donors. Type O negative blood (red cells) can be transfused to patients of all blood types. It is always in great demand and often in short supply. Type AB positive plasma can be transfused to patients of all other blood types. AB plasma is also usually in short supply.
The Nation Has a Major Blood Shortageabcnews.go.com/Health/story?id=117954... A critical shortage of blood has forced the cancellation of elective surgeries in Los Angeles, Philadelphia and Atlanta, the American Red Cross said today. Both the Red Cross and America’s Blood Centers (ABC), which together represent virtually all U.S. blood banks, reported severe shortages at a season when blood supplies are usually adequate. One of Worst Shortages “This is one of the worst ones that the Red Cross has seen,” Red Cross President Dr. Bernadine Healy said in a telephone interview. Healy said 32 of her group’s 36 regions were on appeal, which means either they have less than a day’s supply of blood available or they simply have inadequate supply to meet hospital demand. Those cities in urgent need include Los Angeles, Baltimore, Detroit, St. Louis and Philadelphia, according to the Red Cross. ABC said there were severe shortages throughout the Northeast. Need to Cancel Elective Surgery She said the Red Cross had advised hospitals to cancel elective surgery in Los Angeles, Atlanta and Philadelphia.The reason for the shortage is increased demand, much of it due to the increased number of complex therapies such as chemotherapy, organ transplants and heart surgeries, which require large amounts of blood and blood products, both groups said. Just one liver transplant can use 120 units of donated blood, ABC’s Melissa McMillan said by telephone.The increase in demand far outpaces the increase in blood donations, Healy said, with donations increasing annually by about 3 percent and demand growing at 6 percent. Behind by 40,000 Units The Red Cross needs 80,000 units on hand daily, but now has only about 36,000 a day, according to Healy. “People often forget for how many medical procedures blood is a vital necessity,” Healy said. Blood shortages are common during the summer months, when schools and businesses are less likely to have blood drives, according to spokeswomen for both the Red Cross and ABC. But a crisis in September is unusual and alarming, McMillan said. Shortages Uncommon This Season “Shortages at this time of the year are uncommon,” said McMillan said. “It’s a bit frightening, to be honest.”
Bedankt JHDH. AB voor plaatsen. Er zullen noodzakelijkerwijs steeds meer plasmavrije medicijnen ontwikkeld moeten worden als alternatief voor de bestaande uit bloedplasma geproduceerde geneesmiddelen, zodat bloedbanken bloed en bloedplasma van gezonde bloeddonoren aan ziekenhuizen, Rode Kruis enz. kunnen blijven leveren.
Omdat in Amerika de meeste bloeddonaties door studenten worden gegeven, maakt men zich in de States zorgen over de komende zomerperiode. Wanneer de studenten niet naar school gaan geven ze ook geen bloed.www.krgv.com/story/38043535/valley-bl... Het is te hopen dat ze dit in de toekomst beter gaan regulieren. In China proberen ze het te regulieren, maar werkt mogelijk voor patiënten averechts.www.bbc.com/news/av/world-asia-china-...
Advocates and critics of pay-for-plasma clinics await Health Canada report.www.ctvnews.ca/health/advocates-and-c... de kaarten voor Pharmings ruconest komen steeds beter te liggen..
American Red Cross issues emergency call for donations The American Red Cross is facing a critical blood shortage and has issued an emergency call for donations. The Red Cross says the current shortfall - about 61,000 fewer donations than needed - is the equivalent of not collecting any blood donations for more than four days.www.fox2detroit.com/health/american-r... ook dit telt natuurlijk mee in de Goedkeuring van Ruco profi, immers de Carmarks/CVS willen geen 2/3x een risico aan tekort medicijn lopen..nogmaals Schadeclaims zullen hoog zijn....!!!!
Drug shortages prompt FDA to form task force. The US Food and Drug Administration is forming a Drug Shortages Task Force to look into the country's persistent drug shortages and find long-term solutions, according to a statement Thursday? from the agency's commissioner, Dr. Scott Gottlieb.us.cnn.com/2018/07/12/health/fda-drug... "and find long-term solutions".. ze zullen nu onderhand wel weten dat een tekort aan Ruconest zelden of nooit voor zal komen, dit is ook een bevestiging waarom steeds meer healthcare providers Ruconest op nr 1 zetten als medicijn voor HAE en zodadelijk ter voorkoming also.
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